The innovative pharmaceutical industry is dedicated to ensuring patients receive the medicines they need and supports EU-coordinated efforts to strengthen supply chains and prevent shortages across Europe. However, addressing supply issues is complex and requires tailored solutions. Challenges can arise from various factors, such as manufacturing constraints, limited capacity due to lengthy investment lead times, and unexpected surges in demand from public health emergencies, improved diagnostics, evolving medical practices, forecasting errors, or other factors diverting supply from the patients. Additionally, medicines have diverse production and supply needs; for instance, biological products, vaccines, and plasma-derived therapies often require specialized in-house facilities due to their technical demands. In recent years, EFPIA members have invested in making supply chains more resilient. Our global, geographically diverse network enables us to adapt production and deliver medicines where they are needed most.